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Macrophage activation syndrome in a patient with axial spondyloarthritis on adalimumab

Remarkably, forsythiaside can be considered a prodrug that, upon metabolism, will release a cinnamic acid derivative, which has a modulatory effect on neurotransmitters, as previously discussed

FTH1 alters intracellular iron homeostasis by influencing iron storage and release, and iron imbalance is a major trigger for ferroptosis (71,72)

5 Consequently, rasburicase is contraindicated in patients with G6PD deficiency, as these patients are unable to detoxify the hydrogen peroxide produced in the conversion of uric acid to allantoin