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Gilkerson RW, De Vries RL, Lebot P, Wikstrom JD, Torgyekes E, Shirihai OS, et al

All controls were individually matched to cases by age ( 1 year) at a 1:1 ratio

Arch Dis Child

Whether coupling clip placement with other percutaneous procedures directed toward optimization of other anatomical abnormalities within the mitral apparatus (such as chordal replacement, altering ventricular, or atrial geometry among others) alters the disease course of severe MR remains to be studied and has potential to expand the patient pool that would benefit from such a combination procedure ( Proportionate vs