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Conversely, PLCAR was found to be significantly more effective for alleviating general, physical fatigue and muscular weakness (p = 0.004)

Molec Genet Metab 65 : 264271 Mohsen AW, Anderson BD, Volchenboum SL, Battaile KP, Tiffany K, Roberts D, Kim JJ, Vockley J 1998 Characterization of molecular defects in isovaleryl-CoA dehydrogenase in patients with isovaleric acidemia