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Methods/design The proposed study involves a controlled, randomised, multicentre, parallel, non-inferiority clinical trial lasting one year, involving 23 primary healthcare centres in the Madrid region (Spain), and patients 65 years of age

which was published recently, revealed that 3 g LC per day for 7 days in the liquid form via enteral tube feeding in 54 critically ill patients, improved serum Alb and decreased CRP and IL-6 biomarkers in the LC group in comparison to the placebo group which is in line with our results

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Permeability changes have not been verified yet in the constipation-predominant IBS (IBS-C) subgroup by other investigations, whereas patients with mixed bowel habits (IBS-M) have not been investigated so far