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Chronic prostatitis/chronic pelvic pain syndrome leads to impaired semen parameters, increased sperm DNA fragmentation and unfavorable changes of sperm protamine mRNA ratio

Compounds like catechins, chrysin, pinocembrin, and nobiletin have shown promising antifibrotic and anti-inflammatory effects, directly targeting NLRP3, while others like kaempferol and diosmin exhibit therapeutic benefits through alternative pathways

In the Kmt2d +/Geo mouse model, treatment with KD for 2 weeks normalizes the global histone modification state corrects the neurogenesis deficiency in the granule cell layer of the dentate gyrus, and rescues the hippocampal memory defects (88)

Smith and M