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Description

Direct neuroprotective effects include protection against various neurotoxic insults and support for dopaminergic systems

It crosses the blood-brain barrier efficiently and influences vascular physiology to improve cerebral blood flow, aiding neuronal communication and cognitive functions

M.HardingJ

Based on available Phase 2 data, both agents share a side-effect profile broadly consistent with other medicines acting on metabolic hormone pathways, though the triple-agonist mechanism of retatrutide introduces some additional considerations