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This so-called Na-RALA is significantly more bioavailable (Studies on comparable products have shown a 21-fold increased bioavailability (determined) as a simple, unstabilized R-alpha lipoic acid, as measured by the maximum blood plasma concentration (Cmax), and is also 100% free of S-alpha lipoic acid

The most prominent secondary metabolites identified in the extracts of Curculigo species are phenolic glycosides, phenols, lignan glycosides, lignans, triterpenoid glycosides, triterpenes, polysaccharides (COPb-1 and COPf-1), flavones, aliphatic compounds, alkaloids, eudesmanes, and bioactive proteins (neoculin, curculin, and -amylase) [2].-amylase was purified from the crude extract of C.pilosa [7]

Furthermore, in the tumor microenvironment, lactate can polarize macrophages toward a pro-angiogenic phenotype characterized by vascular endothelial growth factor (VEGF) production, which facilitates tumor progression [107]