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Instrument performance was monitored regularly (approximately every 48 h) using a standard reference sample and an in-house Shiny QC application

MET is a single pass tyrosine kinase receptor essential for embryonic development, organogenesis and wound healing

Prior to eventual internalization by distant immune cells, the formation of MVs, which also contain important immune-cell receptors and inhibitory complement receptors, may contribute to an immune or tolerogenic microenvironment for MM cells in the bone marrow (BM) niche [25] [26]

These mice were maintained in SPF units of the Animal Center of Shenzhen Peoples Hospital with a 12 h light cycle from 8 a.m