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Description

Telomerase activity, mediated by TERT expression, declines in an age-dependent manner, and the ratio of telomere length to telomerase activity provides a molecular measure of cellular aging that complements traditional ovarian reserve markers [192, 216]

the method of the invention comprises administering to a subject a composition comprising an EphA2 or EphA4 targeting moiety attached to a therapeutic or prophylactic agent against the hyperproliferative cell disease