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Frequency varies by study design

* Correspondence: Lin Li, [email protected] Liang, [email protected] Zhang, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Among the ALS-associated genes, multiple mutations have been demonstrated to be strongly correlated with axonal dysfunction (Mizielinska et al., 2025)