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The pattern recurs across every endpoint category: an intermediate biomarker moves in the right direction, but the hard outcome the biomarker is supposed to predict does not follow

the April 2025 Jutras Science Translational Medicine peptidoglycan-persistence paper

Duration of IV infusion

By synthesizing insights from preclinical breakthroughs and early clinical trials, it establishes a roadmap for the development of next-generation radioimmunotherapy, an approach that leverages the cGAS-STING axis to overcome treatment resistance in solid tumors