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Beyond recapitulating established pathways, we dedicate considerable attention to translational implications, systematically evaluating potential therapeutic avenues such as anti-inflammatory modulation, oxidative stress mitigation, and lung microbiota remodeling

The protocol was approved by the IRB of KNUH with informed consent from the legal guardian of subjects aged 2 years and older

The point being, I took two basics

Why pulsatile and endogenous matters Because these analogs stimulate the pituitary rather than replacing GH, the resulting secretion tends to preserve the bodys natural pulsatile rhythm and remains subject to normal feedback control somatostatin, IGF-1 negative feedback, and the finite secretory capacity of the gland