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Table 5 summarizes the pharmacokinetic differences in pregnancy

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Recent work found that -hydroxybutyrate (BHB) enhances mitochondrial function but may exacerbate neuroinflammation by inhibiting histone deacetylases (Sun et al., 2022)

Duloxetine versus placebo in patients with painful diabetic neuropathy

DEM is an alkylating agent but the effect induced on cell proliferation is not due to its alkylating properties since incubation of DEM and GSHe prevented DEM impairment of cell proliferation