glutathione synthetase deficiency blood smear #imageoftheday, 👉 A 24-year-old man develops acute jaundice and dark urine after starting trimethoprim-sulfamethoxazole. A peripheral reveals the specific cellular defects shown. The underlying Frontiers | Usefulness of NGS

Cuglievan B, Kantarjian H, Armstrong S, Rubnitz J, Zwaan M, Dinardo C, Cooper T, Pollard J, Kadia T, Guest E, Short N, McCall D, Daver N, Nunez C, Haddad F, Garcia M, Bhalla K, Maiti A, Catueno S, Fiskus W, Gibson A, Roth M, Khazal S, Tewari P, Abbas H, Bourgeois W, Andreeff M , Gruber T, Shukla N, Truong D, Connors J, Joseph Ludwig J, Stutterheim J, Salzer E, Dam KJ, Sasaki K, Mahadeo K, Tasian S, Borthakur G, Dickson S, Faulk K, Jain N, Jabbour E, Meshinchi S, Garcia Manero G, Ravandi F, Stein E, Kolb A, Issa G

Quick Answer: The best way to absorb glutathione is through liposomal delivery, which uses a protective fatty shell to bypass digestion

Together, our findings demonstrate that WL-1 may be a potential novel antiviral agent against HSV-1 infection-induced facial palsy

Comparison of monoculture and coculture datasets showed little evidence of T cell activation for the T cell (no TCR and no CAR) samples, as expected (Supplementary Figs