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The relationship between ER stress, apoptosis, and autophagy may be that Cr(VI)-induced autophagy rescues Cr(VI)-induced mitochondrial damage by phagocytosis of damaged mitochondria, which consequently reduces apoptosis due to mitochondrial damage, and ER may be the intersection of autophagic and apoptotic pathways ( 3.4 Others Cr(VI) causes cellular ER stress, autophagy, and apoptosis