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Methods: Among the 5174 HBs patients enrolled in the ANRS CO22 Hepather French national prospective cohort between Q3 2012 and Q4 2015, 1162 patients with HBeAg-CI were studied with a median follow-up of 5.8 years (IQR 4-7.2)

Paietta E, Racevskis J, Stanley ER, Andreeff M , Papenhausen P, Wiernik PH

This has implications for the genetic diagnosis of THAP1 dystonia and supports the use of broader strategies like targeted next generation or whole exome sequencing in this population