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Zhang J, Zhang P, Wei Y, Piao HL, Wang W, Maddika S, Wang M, Chen D, Sun Y, Hung MC, et al

In this review, we integrate the ubiquitination and deubiquitination processes with the 14 hallmarks of cancer

The L-reduced form is the biologically active one

Cisplatin activates the MEG3/NLRP3/caspase-1/GSDMD pathway to induce pyroptosis in triple-negative breast cancer (TNBC), thereby inhibiting tumor growth and metastasis [41]