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10.1053/j.ajkd.2014.09.023 26 HuD

A comparative analysis of our eosinophil dataset with available bulk RNA-seq data (Wang et al, 2022) and the few existing scRNA-seq profiles of eosinophils (Chhiba and Kuang, 2024

These discrepancies can be traced back to very low amounts of CYPs within the human lung and their specific distribution regarding different cell types of lung tissue.[ 45 , 71 ] Besides CYPs a great variety of other enzymes are found in the lung, including EPHX (epoxide hydrolase), NQOs (quinone oxidoreductase), STs, and GSTs (glutathione transferase), [71] which is not surprising since the lung forms one of the first lines of defense against inhaled xenobiotics