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When mitochondrial glutathione is depleted, energy production becomes less efficient and mitochondrial DNA accumulates mutations a process associated with aging and age-related diseases

The compounds and mechanisms are unrelated

Real-world example: This distinction explains why someone who skipped a glass of water at dinner probably isnt experiencing a meaningfully different BAC than if theyd had that glass but someone who spent three hours in the sun at a summer festival without drinking any water, then started drinking alcohol, is in a genuinely different physiological state