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Description

In aquaculture industry, the demand of prebiotics supplements increasing continuously for few decades

When activated, Nrf2 translocates to the nucleus and promotes the expression of antioxidant and cytoprotective genes

Direct comparison of differentially expressed genes (DEGs) in our dataset to previously published datasets revealed that genes upregulated in amdh-1 mutants were also highly upregulated in skn-1(lax188) gain-of-function animals and downregulated in worms treated with skn-1 RNAi (fig 1f) (Nhan et al., 2019

However, many challenges and unknowns concerning how to modulate oxidative stress for further practical clinical applications exist, and more targeted research is needed