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Distrbios cognitivos (ateno, memria, concentrao)

22q11 Deletion Syndrome (DiGeorge Syndrome) : Associated with cleft palate cleft lip, cardiac defects, thymic hypoplasia, and hypocalcemia due to parathyroid hypoplasia (Tijare , 2012)

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TARDBP is the gene encoding TDP-43 and leads to TDP-43 aggregates, similar to findings in nongenetic ALS, thus making it an intriguing target for intervention