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During the stress phase, myocardial blood flow is increased using: Exercise stress, like testing on a treadmill or bike, while keeping an eye on the patients heart rate with an EKG Pharmacologic stress, employing agents such as Lexiscan (regadenoson) or adenosine At the height of stress, a radiotracer like technetium-99m sestamibi or tetrofosmin is injected

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In the CY 2024 PFS proposed rule, CMS solicited comments on potential changes to payment for skin substitutes