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The effect of low-grade endotoxemia on the risk of atherosclerosis has been evaluated in various prospective studies, where significantly increased risk has been demonstrated in patients with high LPS concentrations [62]

In such cases, reduced availability of L-arginine limits its ability to act as a substrate for eNOS, favoring the production of ROS over that of NO (Yang and Ming, 2013)

The instrument was configured as follows: GFP (excitation: 488 nm, 530/30 nm bandpass filter), mCherry (excitation: 561 nm, 610/20 nm bandpass filter), and DAPI (excitation: 355 nm, 450/50 nm bandpass filter)

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