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These include: Vegetarians and vegans, as vitamin B12 is mainly found in animal products Older adults, as they absorb vitamin B12 less well with age People with gastrointestinal disorders, like celiac disease or Crohns disease, which can block vitamin B12 absorption Those taking certain medications, such as proton pump inhibitors or metformin, which can also block vitamin B12 absorption Its best to talk to a healthcare professional about whether you need vitamin B12 supplements

Patients should start with a low dose and increase gradually under medical supervision to minimize side effects

Coverage depends on your specific insurance plan

ENS can not only interact with microbiota, metabolites, and nutrients, but also interact with immune cells and inflammatory factors to jointly maintain intestinal homeostasis (Rao and Gershon, 2016)