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Accessed 1/3/2024, Harris WS, Del Gobbo L, Tintle NL

Banh RS, Kim ES, Spillier Q, Biancur DE, Yamamoto K, Sohn ASW, et al

Because cellular iron output is mediated by FPN1 and polycupric ferrous oxide enzymes (such as ceruloplasmin), a decrease in the expression of FPN1 or ceruloplasmin can increase the sensitivity of cells to ferroptosis [29,30,31,32]