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Conventional medical workups reveal nothing abnormal, and they are often told to simply reduce stress. This frustrating experience leaves many searching for answers, where they inevitably encounter the popular but misleading concept of adrenal fatigue. The truth is, the constellation of symptoms associated with chronic burnout is not a failure of the adrenal glands themselves, but a breakdown in the complex communication system that governs our stress response

PC ensures sufficient anaplerosis to sustain glutamine synthesis (Figure 1) (discussed in detail below)

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J Am Soc Nephrol 13(6):14251432 Vrignaud P, Semiond D, Lejeune P, Bouchard H, Calvet L, Combeau C et al (2013) Preclinical antitumor activity of cabazitaxel, a semisynthetic taxane active in taxane-resistant tumors