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Store lyophilized material at 4 F (20 C) or below Allow vial to reach room temperature before opening Protect from light, heat, and humidity Use sterile laboratory equipment during preparation Avoid repeated freezethaw cycles Label reconstituted samples with preparation date and concentration Following these practices supports reliable peptide handling and experimental reproducibility

In genetically susceptible individuals, these peptides are deamidated by tissue transglutaminase, presented mainly by HLA-DQ2 or HLA-DQ8, and drive both innate and adaptive immune activation

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The global incidence of RA is approximately 1%, and two thirds of the cases are women [3]