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There is very low-quality evidence that bupropion, an antidepressant and antismoking agent that inhibits catecholamine re-uptake, may produce small reductions in methamphetamine use and craving [23]

Suppression of YAP/TAZ-Notch1-NICD axis by bromodomain and extraterminal protein inhibition impairs liver regeneration

Trials show improved healing vs placebo and outcomes comparable to topicals

In one example, an amino acid in a polypeptide encompassed by the invention is substituted with another amino acid having similar structural and/or chemical properties, e.g., a conservative amino acid substitution