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This transporter is densely expressed in astrocytic processes abutting glutamatergic and GABAergic neurons (Boulland et al., + concentrations (Brer et al., + in astrocytes during re-accumulation of excess extracellular K + from the extracellular space after neuronal excitation (Xu et al., 2013) might therefore increase glutamine release

EBioMedicine 98:104873, 2023

These phenotypes are accompanied by enhanced oxidative metabolism and reduced adipose tissue inflammation, highlighting a critical role for GPR146 in promoting white adipose tissue expansion and metabolic dysfunction under conditions of nutritional excess

Methylcobalamin is the form of B12 that your body can use most effectively, especially for those with methylation issues