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In ovariectomized rats, mitochondrial oxygen consumption rate in skeletal muscle decreases by ~25% at rest, with maximal respiratory capacity reduced by up to 40% (123)

As stated, OspA is a well-studied LD vaccine antigen that has been proven to protect against Bb infection after tick and needle challenge studies

499 This clinical trial is based on a proposed mechanism that sodium selenate acts as a specific agonist for PP2A, one of the implicated phosphatases in regulating tau protein phosphorylation

Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions