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CDK4, cyclin-dependent kinase 4

Curr Biol 8:6981 Burnett PE, Barrow RK, Cohen NA, Snyder SH, Sabatini DM (1998) RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

A compensatory anti-inflammatory mechanism then typically follows (59), causing an imbalance in immune responses (58, 59) combined with hypothesised autoimmunity (52, 85, 182)