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Some symptoms of vitamin B12 deficiency include: Weakness and tiredness Pale or yellowish skin Loss of appetite Heart palpitations Mouth or tongue soreness Tingling or "pins and needles" sensation in your hands and feet Shortness of breath Dizziness Blurry vision Mood swings or personality changes You are more at-risk for developing vitamin B12 deficiency if you are: Pregnant Over 65 Vegan Take medicine for diabetes Take medicine for heartburn Have had surgery to remove part of your bowels Health News Agencies In New York And Beyond Pass The Buck On Opioid Cash Oversight How Does ADHD Affect Athletes' Concussion Risk

Annexin-V is a protein that binds to phosphatidylserine, which usually presents only on the inner layer of the cellular membrane

Finally, THAP11 deficiency (Quintana et al., 2017) and ZNF143 deficiency (Pupavac et al., 2016) also affect the transcriptional regulation of MMACHC

doi: 10.1016/j.actbio.2020.01.016 235 GoldbergRKleinJ