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Usually, as with other drug evaluations, the placebo-adjusted treatment effect (i.e., the difference between weight losses with pharmacotherapy and placebo, when given as an adjunct to lifestyle intervention) is provided from data in randomized clinical trials (RCTs)

25 Throw cold water on If you throw or pour cold water on something you point out what is wrong with it instead of enjoying it or its idea with other people

Same-day appointments typically available No referral needed Feeling tired, run down or low on energy