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Yeungnam Univ J Med 38(1):1018

in fact, human cells and in particular neurons and mitochondria are equipped with a specific transporter (SLC22a4) of ergothioneine

10.3389/fpls.2015.00420 37 HruzT.LauleO.SzaboG.WessendorpF.BleulerS.OertleL.et al

Depletion of cellular GSH by deletion of the essential -glutamylcysteine synthetase also led to Aft1 activation and impaired cytosolic FeS cluster enzyme activity, which could be partially restored with exogenous iron (