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doi: 10.3389/fnut.2025.1581848 Received 23 February 2025 Accepted 22 September 2025 Published 15 October 2025 Volume 12 - 2025 Edited by Roberta Zupo, University of Bari Aldo Moro, Italy Reviewed by Padhmanand Sudhakar, Kumaraguru College of Technology, India Edem E

Stockler-Pinto MB, Mafra D, Farage NE, Boaventura GT, Cozzolino SM

When oxidized, it forms into a form known as a dimer (GSSG), and after interaction with a reducing agent such as vitamin C, can returned to the active state, without loss of function

Research also shows that the GI tract adapts to GLP-1 receptor agonism through receptor desensitization