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10.1074/jbc.m115.684969 20 GunaratnamS.MilletteM.McfarlandL

Pat No 6,747,009 of the formula I: wherein Z=CH 2 and Y=CH 2 , or Z=O and Y=C, Ri and R 2 are independently selected from the group consisting of H, linear or branched alkyl (1-25C), aralkyl (6-26C), cycloalkyl (6-25C), heterocycles (6-20C), ethers or polyethers (3-25C), and where Ri-R 2 together have 2-20C atoms and form a macrocycle with the remainder of formula I

Development 126 , 31313148 (1999)

Indeed, great efforts have been made in the field over the past two decades to search objective biomarkers to inform the diagnosis of ASD, especially biomarkers from blood since it is easily accessible and inexpensive