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Description

By selectively inhibiting NNMT , 5-Amino-1MQ can reduce the methylation of nicotinamide, leading to increased intracellular NAD availability and enhanced metabolic activity

Trends Endocrinol Metab 21:610618

Clinical data is not

Treatment with SLU-PP-332 increases expression of mitochondrial biogenesis and oxidative phosphorylation genes, leading to enhanced mitochondrial function, oxygen consumption, and ATP production