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Immunohistochemical analysis also revealed a significant decrease in the hepatic expression of both proapoptotic markers Bax and caspase-3 with significant increase in antiapoptotic Bcl-2 expression in rats treated with NTZ-200, NAC or 4-PBA when compared to MTX group (Figure 9)

The imperative lies in rigorous research endeavours, particularly well-executed randomized controlled trials, to address current methodological limitations

Because of the way patents for small peptides work, anyone can make a small change to a molecule, adding one amino acid here or there and now have a competing product that would not fall under the patent

Kodeboyina, S