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10.4251/wjgo.v12.i2.149 105

Effects on cognition and global function were evaluated with the Alzheimers Disease Assessment Scale Cognitive Subscale (ADAS-Cog) and the Clinician Interview-Based Impression of Change with Caregiver Input scale (CIBIC+) at 4, 12, and 24 weeks after the start of injections

Lung cadmium content was determined by inductively coupled plasma-mass spectrometry (ICP-MS) analysis, and TOPO-PMAT QD disposition was modeled using PKSolver as described in Methods