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Toxigenesis is the capacity to produce toxins that are categorized into exotoxins and endotoxins according to their sources, nature and roles (de Nies et al., 2021)

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[Abstract]2024 Feb 20:912:169260

In CRC, immune checkpoint inhibitors (ICIs) primarily act by blocking the interaction between programmed cell death protein 1 (PD-1) and its ligand PD-L1, and also by inhibiting the function of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) (Jiao et al., 2020)