mark gordon glutathione Frontiers | Glutathione and neurodegenerative

When to Seek Medical Advice About B12 and Joint Symptoms Knowing when to contact your GP or healthcare provider regarding joint symptoms in the context of B12 supplementation is essential for ensuring appropriate investigation and management

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Intramuscular replacement therapy is indicated for patients with: Significant B12 deficiency (thresholds depend on local laboratory reference ranges) Neurological symptoms or signs Pernicious anaemia Malabsorption syndromes The standard UK regimen for patients without neurological involvement involves hydroxocobalamin 1mg intramuscularly three times weekly for two weeks, followed by maintenance injections every 2-3 months (often 3-monthly)

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