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Description

Sponagel J, Jones JK, Frankfater C, Zhang S, Tung O, Cho K, et al

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The integrated analysis of the experimental X-ray crystallography data herein presented with computational analysis and literature data on homologous enzymes strongly supports the identification of at least two druggable sites on SmTGR, i.e., sites S3 (doorstop) and S8, the later described for the first time here

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This is particularly important because glutathione is quickly metabolized in the body, and a steady supply is needed to support its many functions

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In particular, the cell adhesion molecules, including ICAM-1 (intercellular adhesion molecule 1) and HCAM (homing Key Points Lay Summary Biomarkers as a Diagnostic Tool By Kasthuri Nair Ahn, Singh and Tayade discuss the difficulties and delay in diagnosing Endometriosis in their paper titled Biomarkers in endometriosis: challenges and opportunities. Thus far research has identified a multitude of potential biomarkers that are found in various parts of the Key Points Lay Summary

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