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237,238 Autophagy, mitophagy, and therapy resistance Autophagy and mitophagy critically influence therapeutic resistance

Similarly, another study demonstrated no difference in the VPT between the treatment and placebo groups.(11) Only one study demonstrated statistically significant (p = 0.006) improvement in the nerve conduction velocity of the peroneal nerve by 1.1 m/s compared to that of the placebo group, which dropped by 2.7 m/s.(13) This same study also showed a statistically upward trend in the VPT, approaching a mean of 1.4 m at week 12 of treatment compared to 2.0 m at baseline.(13) Of the three studies that looked at neuropathic symptoms as a primary outcome measure, only one showed improvement in this aspect