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The evidence that a strong influence of SO 2 and, to a lesser extent, of GSH, was observed is further confirmation that these compounds are very reactive in inhibiting the Fenton formation of aldehydes and that they also prevent reactions with anthocyanins by diverting the aldehydes to bound forms

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Animal experiments and studies of human subjects have shown that IOP-independent factors include oxidative stress, glutamate excitotoxicity, and impaired retinal blood flow 6,7,8

Potential miRNA-based interventions include restoring or suppressing miRNA activity using synthetic mimics or inhibitors (anti-miRs) (101, 102)