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Understanding whether B12 supplementation will meaningfully support your semaglutide treatment requires more than a simple yes-or-no answer

But here are few common signs of vitamin B12 deficiency: Tiredness, fatigue or weakness Numbness or tingling in the hands or feet Memory issues or loss of concentration Constipation Muscle weakness Dizziness NOTE: These are some signs of B12 deficiency that can benefit from a B12 regimen

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Low levels of B12 could potentially lead to a decrease in the production of serotonin ultimately causing or contributing to depression