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For any injectable, microneedling and/or topical product: we advise that you conduct a patch test and wait in accordance with manufacturer advice (as per the product's packaging and/or enclosed literature) before proceeding to use it

By optimizing extraction yields and protecting bioactives from degradation, these technologies improve cost efficiency and reduce food waste, making functional food production more economically viable

Furthermore, only four studies reported MCID thresholds, and none performed responder analyses beyond the 50% VAS reduction criterion (Shokri et al., 2021

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