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48, D1104D1113

The SILEX system is compatible with all classical culture media and growth temperatures and allows protein expression modulation

Knockout of the enzyme which synthesizes GPE, phosphatidylserine decarboxylase Psd1 (mammalian Pisd), in yeast and worm models of PD was shown to result in the formation of -syn foci, ER stress, defects in trafficking, and decreased respiration (Wang et al., 2014)