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199 , e0045316 (2016)

14), these amplification factors were 7.5 (BME) and 4.75 (PureCol EZ Gel)

We hypothesize that ArfGAP1 could mediate LRRK2-induced toxicity either by i) serving upstream as a GAP-like protein to enhance the GTPase activity of LRRK2, or ii) serving downstream as a substrate of LRRK2-dependent phosphorylation