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A weakly informative prior for between-trial heterogeneity ( ), specifically an HN prior with a scale of 0.5, was applied 29 , whereas uninformative priors were used for treatment and interaction effects

Arginine deficiency leads to limited activation of immune cells such as T cells (146) and NK cells (147), thereby impairing the immune response and promoting tumour development and metastasis

Many trials recruited younger participants outside our target demographic of 3065 years, limiting the available evidence for middle-aged and older adults

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