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As the integrity of subcellular membranes depends heavily on GP, which in turn depends on selenium, the mechanism of GP is at the Selenocystein site, in a Se - form at resting state

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Clinical Features Friedreichs ataxia (FRDA) is a rare, autosomal recessive neurodegenerative disorder characterized by progressive limb and gait ataxia, primarily affecting the spinal cord, cerebellum, and brainstem

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